Sirtuins and neuronal DNA damage under experimental chronic cerebral hypoperfusion

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Chronic cerebral hypoperfusion and impaired neuronal function in rats.

BACKGROUND AND PURPOSE Studies in acute cerebral ischemia have shown that reductions in cerebral blood flow of up to 50% do not lead to infarction or alterations in neuronal electric activity. Little is known about the effects of chronic reductions in cerebral blood flow. The purpose of this study was to evaluate neuronal electrophysiological function in brain that had been subjected to a chron...

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ژورنال

عنوان ژورنال: Pathologia

سال: 2019

ISSN: 2310-1237,2306-8027

DOI: 10.14739/2310-1237.2019.2.177121